Necessary analyses for the understanding cellular mechano-signal transduction mechanisms in biological tissues: the articular cartilage paradigm 理解生物组织细胞力学信号传导机制的必要分析:以关节软骨为例
The cellular events of intramembranous ossification, cartilage formation, endochondral ossifications, and bone remodeling appear in the callus simultaneously or sequentially. 骨痂内的膜内化骨,软骨形成,软骨内化骨和骨重建等过程可同时或连续出现。
To discuss the best cellular density and culture time in cartilage tissue engineering which use BMSCs as seeding cell and collagen I as scaffolds. 探讨以人骨髓间充质干细胞为种子细胞、Ⅰ型胶原凝胶为载体的软骨组织工程的最佳细胞密度和最佳培养时间。
It is very difficult to realize reasonable interaction among seeding cell, growing factors and cellular scaffolds, so there is no satisfied method that can product tissue-engineering cartilage to repair cartilage defects at present. 但由于难以实现种子细胞、生长因子及基质材料三者间的合理相互作用和各种疾病复杂的病理过程,目前尚无一种组织工程学方法能高质量地修复软骨缺损并达到很好的远期疗效。